Nerve Fresh: What It Is, What It Costs and Where to Buy It

What is on the label

The Supplement Facts panel lists five herbs, per serving of two capsules:

That is all. The marketing also mentions vitamin and mineral support, but no vitamin or mineral is on the label, and one FAQ lists prickly ash bark, a different plant, instead of prickly pear. Go by the label.

The serving is two capsules, so a bottle of 60 lasts a month, although one sales page calls it one easy daily capsule. The corydalis is a 10:1 extract, which means 200 mg was made from about 2 g of root, and the California poppy is also an extract; the marshmallow root and prickly pear are listed as powders.

Illustrations by Health and Wellness Studies, not to scale.

What the research shows, at a glance

Nerve Fresh itself has never been tested in a published study, so these ratings are for its five herbs, from the studies in our full review:

• Corydalis: in 2014, researchers at the University of California, Irvine, found that a compound from the plant, dehydrocorybulbine, eased inflammatory and nerve-injury pain in mice. We found no trial of corydalis in people with neuropathy.
• Passionflower: a 2020 systematic review of nine short trials found that most reported less anxiety, but a Cochrane review said the anxiety trials were too few to draw conclusions. The nerve-pain study offered for it was in rats.
• California poppy: used traditionally as a sedative and sleep aid; no trial in neuropathy.
• Marshmallow root: a traditional remedy for sore throats and coughs; no nerve research in people.
• Prickly pear: studied as a food for blood sugar, in far larger amounts than 100 mg; no nerve research in people.

Three calming herbs and nerve-pain medicines

Passionflower, California poppy and corydalis are all used as calming or sleep aids. That may explain why some people feel calmer or sleep better on Nerve Fresh. It also matters if you already take medicines that cause drowsiness:

Together with gabapentin, pregabalin, sleeping pills, opioid painkillers or alcohol, they may add to drowsiness, and drowsiness plus numb feet raises the risk of falls. Ask your doctor or pharmacist before combining them.

Who should avoid it, or ask first

• Liver: corydalis has been linked to liver injury. In a 2023 report, two people developed liver problems while taking a corydalis sleep aid, and their liver tests returned to normal after they stopped. Stop and see a doctor if you notice yellow skin or eyes, dark urine or unusual tiredness.
• Sedating medicines: gabapentin, pregabalin, sleeping pills, opioids and alcohol, as above.
• Pregnancy and breastfeeding: there is no safety evidence for these herbs, so avoid it.
• Driving: see how it affects you before driving or operating machinery.

The FAQ says there are no side effects. With three sedating herbs and a liver caution, that is not a claim we can support.

What actually helps neuropathy

Neuropathy has many causes, including diabetes, low vitamin B12, alcohol and some medicines. Treating the cause early may limit lasting damage, which is why a doctor’s visit comes first:

See a doctor promptly, rather than trying a supplement first, if:

• Symptoms spread quickly over days or weeks, or move up from the feet towards the knees.
• You notice weakness, such as tripping, a foot that slaps down or trouble gripping.
• A foot sore will not heal, or a numb foot becomes red, hot or swollen.
• Symptoms began after a new medicine, such as some chemotherapy or antibiotics.

Our neuropathy guide explains what the research shows for supplements and medicines.

How Nerve Fresh is marketed

• Two doctors, one career: one sales page credits the formula to a podiatric surgeon. The company’s other site credits the same formula, with the same credentials and awards, to a different doctor, a medical doctor we could not find in the US national register of healthcare providers.
• “Ditch Gabapentin”: a written headline tells readers to drop the medicine. As above, stopping it suddenly can be harmful.
• Three “enzymes”: the page says the formula silences COX-2, PGE-2 and MMP-13. PGE2 is a prostaglandin, not an enzyme, and the MMP-13 research cited was done in zebrafish given chemotherapy.
• Seals and logos: the page shows a USP Verified seal, but Nerve Fresh is not on USP’s own list of verified products, and it shows TV and newspaper logos without saying what was featured.
• The refund policy refers to the product by a different name, apparently copied from another product.

Which package makes sense?

There is no single bottle. Two bottles cost $138 ($69 each), three cost $177 ($59 each) and six cost $234 ($39 each), all with free shipping; the three- and six-bottle packages add two e-books. It is a one-time payment, with no monthly charges.

• Two bottles ($138) are the smallest order, enough to see how the herbs affect your sleep, alertness and any medicines.
• Six bottles ($234) are the cheapest per bottle, at $1.30 a day, but the refund policy refuses empty bottles unless enough time has passed to use them, so six empties after a month or two would not be refunded.

How to take it, if you try it

• The dose: two capsules a day, as the label says, not more.
• Evening may suit you better, since three of the herbs are calming; see how it affects you before driving.
• Keep taking your prescribed medicines, and tell your doctor or pharmacist you have added it.
• Stop and see a doctor if you notice yellow skin or eyes, dark urine, unusual tiredness or heavy drowsiness.
• Keep checking your feet daily if they are numb.

How the 180-day refund works

1. Email or call support first, and keep your order number.
2. Send the bottles back to the returns warehouse in Aurora, Colorado. You pay the return postage, and they must arrive within the 180 days.
3. Empty bottles are accepted only if enough time has passed to use them, so do not expect a refund on six empties after one or two months.
4. If you get no reply, ClickBank’s order support at clkbank.com can help, because ClickBank processed the payment.